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Tylenol Autism ADHD Lawsuit Facts
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Recent scientific evidence produced by health professionals in respected institutions have found that prenatal acetaminophen exposure may result in an increased risk to develop Autism Spectrum Disorder (ASD) later in life.
Scientific studies have been conducted involving expectant mothers and their acetaminophen use, later following-up with children and their diagnoses.
These scientific and medical research studies may only skim the surface of the potential issue at hand. The scientific and medical validity of these studies has been debated, but researchers are insistent on their discoveries.
As the medication is so widely available and used, and research efforts have been relatively novel, we’ll only find more out about the potential links between Tylenol and Autism.
We are already aware that rates of Autism are increasing, but the causes of these increases have been debated.
While screening for developmental disorders has become more advanced and sensitive, researchers are pondering whether other environmental factors could have an influence on the increased rates of Autism over the past few decades.
Paracetamol use during pregnancy — a call for precautionary action
Researchers from the University of Massachusetts, Yale University, Icahn School of Medicine at Mount Sinai, University of Aarhus, and others published this September 2021 paper in Nature Reviews: Endocrinology.
The researchers call for more scrutiny of paracetamol (acetaminophen), stating that prenatal exposure to the drug might alter fetal development, which could increase the risks of neurodevelopmental, reproductive and urogenital disorders.
The paper goes on to state that there has been a noticeable increase of diagnosed developmental disorders in children in recent years, along with an increase in the use of Tylenol (acetaminophen) during pregnancy. Up to 65% of expectant mothers in the United States use the medication.
Johns Hopkins University 2019 Study
Researchers from Johns Hopkins University studied the Cord Plasma Biomarkers, the blood in umbilical cords, and found that babies exposed to acetaminophen were two times more likely to be diagnosed with a developmental disorder.
The researchers used the Boston Birth Cohort, studying over 3,000 mother-infant pairs, 996 of which contained children who were later diagnosed with developmental disorders. The research study looked at children from 6 months of age up until 21 years-old.
Researchers defined the level of acetaminophen in cord plasma biomarkers using liquid chromatography–tandem mass spectrometry techniques at the Broad Institute Metabolite Profiling Laboratory at Massachusetts Institute of Technology. Later, the levels of acetaminophen in blood samples could be correlated with the rates of Autism and ADHD diagnosis amongst participants.
The research methods used in this study have come under some scrutiny, as the levels of acetaminophen in blood samples were measured only after the baby was delivered and not throughout the pregnancy.
Prenatal Exposure to Acetaminophen and Risk for Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis of Cohort Studies
Israeli researchers conducted a meta-analysis of seven studies that totaled over 130,000 mother-child pairs and concluded that children of mothers who used acetaminophen during pregnancy had a 20% higher risk of Autism and a 30% higher risk of ADHD diagnoses.
These findings echo other studies that found an increased risk of neurological impacts on children of mothers who used acetaminophen or Tylenol during pregnancy.
